Browsing by Author "Salech Morales, Felipe"

Now showing items 1-5 of 5

    • Cancer imprints an increased PARP-1 and p53-Dependent resistance to oxidative stress on lymphocytes of ... 
      Salech Morales, Felipe; Ponce, Daniela P.; San Martín Rovirosa, Carol; Rogers Castillo, Nicole; Henríquez, Mauricio; Behrens Pellegrino, María Isabel (Frontiers Media, 2018)
      We have proposed that a common biological mechanism deregulated in opposite directions might explain the inverse epidemiological association observed between Alzheimer's disease (AD) and cancer. Accordingly, we showed that ...
    • Klotho: un nuevo eslabón en la fisiopatología de la insuficiencia renal crónica 
      Salech Morales, Felipe; Couve Correa, Andrés; Michea Acevedo, Luis; Alvo Abodovsky, Miriam (Hospital Clínico Universidad de Chile, 2010)
      Klotho, a recently described gene, is mainly expressed in the kidney, and encodes a proteinnecessary for the activity of fibroblast growth factor receptors (FGFR), especially FGFR1. TheKlotho protein has two variants, a ...
    • Multiple events case-control study in a prospective cohort to identify systemic, cellular, and molecular ... 
      Correa Burrows, María Paulina; Burrows Argote, Raquel; Albala Brevis, Cecilia; Court, F. A.; Salech Morales, Felipe; Sanhueza Olivares, Guillermo; González Billault, Christian (BMC, 2022)
      Background Aging is characterized by a progressive loss of capacities linked to fundamental alterations/damage in multiple cellular and molecular pathways. It is the most significant risk factor for all non-communicable ...
    • Rol de Klotho en la regulación de la neurogénesis hipocampal del adulto 
      Salech Morales, Felipe (Universidad de Chile, 2015)
      La población mundial envejece en forma acelerada. Considerando que el deterioro cognitivo es uno de los principales determinantes de enfermedad y discapacidad de los adultos mayores, la comprensión de sus mecanismos f ...
    • Thalidomide for the treatment of metastatic hepatic epithelioid hemangioendothelioma: A case report with a ... 
      Salech Morales, Felipe; Valderrama, Sebastián; Nervi, Bruno; Oksenberg Reisberg, Dan; Rodríguez, Juan Carlos; Smok Sahid, Gladys; Koch, Alvaro; Duarte, Ignacio; Pérez Ayuso, Rosa María; Jarufe, Nicolás; Martínez, Jorge; Soza, Alejandro; Arrese, Marco; Riquelme, Arnoldo (MEXICAN ASSOC HEPATOLOGY, 2011-03)
      Hepatic epithelioid hemangioendothelioma (HEH) is an unusual, low-grade malignant vascular tumor of the liver. Here we describe a case of a 40-year-old woman who presented with abdominal pain in the upper right quadrant ...